Sugar acids and derivatives
![Medchemexpress LLC 7-chloro-3-(2,4-dimethoxyphenyl)-5-methyl-thiazolo[4,5-d]pyrimidine-2-thione | 2459916-56-2 | 98.5% | 353.85 g/mol | C14H12ClN3O2S2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000286978.png-250.jpg)
Medchemexpress LLC 7-chloro-3-(2,4-dimethoxyphenyl)-5-methyl-thiazolo[4,5-d]pyrimidine-2-thione | 2459916-56-2 | 98.5% | 353.85 g/mol | C14H12ClN3O2S2 | 10 MG
CDK1/Cyc B-IN-1 is a small-molecule inhibitor selective for the CDK1-cyclin B kinase complex. It inhibits CDK1-cyclin B activity (reported IC50 ≈97 nM) and induces G2/M cell-cycle arrest and apoptosis in cancer cell lines. The compound is supplied as a solid with high purity and is used in biochemical and cellular studies of cell-cycle regulation.
- Selective CDK1-cyclin B inhibitor with reported IC50 ≈97 nM.
- Induces G2/M cell-cycle arrest and apoptosis in cell lines.
- Suitable for biochemical kinase assays and cell-based studies.
- High supplied purity for reproducible results.
- Soluble in DMSO at 100 mg/mL; use newly opened DMSO.
- Stable as a powder under recommended cold storage conditions.
Medchemexpress LLC Integrin alpha 5 bet 100ug
ITGA5 is a multifunctional receptor that interacts with multiple ligands such as fibronectin fibrinogen PLA2G2A fibrillin-1 (FBN1) IL1B human metapneumovirus and soluble CD40LG ITGA5 recognizes RGD sequences and mediates cell adhesion through different binding sites Integrin alpha 5 beta 1 Protein Human (Biotinylated HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha 5 beta 1 protein expressed by HEK293 with C-Avi C-His labeled tag Integrin alpha 5 beta 1 Protein Human (Biotinylated HEK293 His-Avi) has molecular weight of 110-140 kDa
Medchemexpress LLC 4-methylumbelliferyl α-L-iduronide | 66966-09-4 | MFCD00135894 | ≥99.0% | 352.29 g/mol | C16H16O9 | 500 UG
4-Methylumbelliferyl α-L-iduronide is a fluorogenic reagent used as a sensitive substrate for α-L-iduronidase and related lysosomal enzyme assays. Enzymatic hydrolysis releases 4-methylumbelliferone, permitting fluorescence-based detection and quantitation in biochemical and cell-based assays.
- Fluorogenic substrate for α-L-iduronidase assays.
- Enables sensitive fluorescence detection and quantitation.
- High purity (≥99.0%) suitable for biochemical applications.
- Available in small research quantities (for example, 500 μg) for assay development.
- Stable solid form for convenient storage and handling.
TARGETMOL CHEMICALS INC BLEOMYCIN SULFATE 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Bleomycin Sulfate (Blenoxane) a glycopeptide antibiotic is an anticancer agent for squamous cell carcinomas (SCC). In UT-SCC-19A cells the IC50 of Bleomycin Sulfate is 4 nM. purity: 99%
Medchemexpress LLC Odn D-SL03 (sodium) | 1198621-85-0 | 98.6% | 9345 (free acid) | 10 MG
ODN D-SL03 sodium is a C-class CpG oligodeoxynucleotide TLR9 agonist supplied as a solid for research use. It stimulates peripheral blood mononuclear cells (PBMCs) to produce interferon-α, activates human B cells, NK cells, and mononuclear cells, and modulates antigen-presentation markers. The oligonucleotide sequence is 5'-tcgcgaacgttcgccgcgttcgaacgcgg-3'.
- Stimulates PBMCs to produce high levels of IFN-α.
- Activates human B cells, NK cells, and mononuclear cells.
- Up-regulates CD80, CD86, and HLA-DR expression on immune cells.
- Sequence-defined oligonucleotide: 5'-tcgcgaacgttcgccgcgttcgaacgcgg-3'.
- High purity (98.6%) suitable for research applications.
- Supplied as a solid with recommended storage at -20°C; in solvent, -80°C up to 6 months.
- Available in small amounts appropriate for assays (e.g., 10 mg).
- For research use only.
Medchemexpress LLC Integrin alpha V beta 5 protein | >95.0% | 20UG
Integrin alpha V beta 5 Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant human integrin αVβ5 dimer expressed in HEK293 cells and supplied biotinylated with C-Avi and C-His tags. It is provided in microgram quantities and intended for receptor-ligand interaction studies, biochemical assays, and biophysical analyses that require the native extracellular domains.
- Biotinylated C-Avi and C-terminal His tags for detection and capture
- Expressed in HEK293 cells to preserve mammalian post-translational modifications
- High purity >95% as determined by reducing SDS-PAGE
- Molecular weight range 85-140 kDa consistent with heterodimeric extracellular domains
- Available in multiple microgram sizes to suit different assay scales